Compress weeks of biophysics into a few routine runs.

Fida Evolve resolves molecular size, binding, and sample characteristics from one in-solution diffusion profile - replacing a stack of complementary assays with a single experiment. Multiple questions, one assay. Data gaps closed in the same run that raises them. Routines that used to take days, finished in minutes.

Robustness and confidence of

3 simultaneous measurements

High data yield

10 biophysical readouts

Early binder screening and ranking with

1-minute Kd
Multiple readouts per run
Fewer runs
Faster time to insights
Faster desicions
Higher ROI

Fida Evolve:

Our new multiparameter FIDA biophysics platform enables you to collapse weeks of biophysical analyses into a few days work.

Developed for Complex Samples and New Modalities:

For FIDA the sample environment is context, not obstacle. It allows you to increase biological relevance by handling unpurified samples, high-background matrices, and heterogeneous populations, distinguishing bound/unbound species and oligomeric states without separation steps.

Delivers binding data in context of sample integrity:

By reporting binding alongside aggregation, size, and quality metrics from the same assay, FIDA eliminates ambiguity caused by fragmented assays.

Wide Affinity & Kinetic Range:

Measures dissociation constants from picomolar (pM) to millimolar (mM), and kinetic processes from seconds to hours, covering weak binders, fragments, or biologics alike.

Sample and time efficient:

nL–µL sample sizes, no need for purification, multiple simultaneous readouts & calibration-free operation - all this combined with AI-compatible data reporting allows you to efficiently move frontiers.

FIDA in numbers

Over

10

Characterization parameters

Affinity of

pM - mM

Strong and weak binders

40 nL Analyte

Down to nL sample volumes

Kinetics

Sec-hrs

Fast and slow

Size accuracy of

1%

Size change

2 x 96 samples

Fully Automated

Between

100mM - 10pM

Binding affinities

3 Wavelengths available:

480nm, 640nm or 280nm LED

Size detection of

0.5 - 500nm

Size Range

Size-based quality control: a wealth of information to accelerate your research

Size measurements are the fundament for over 10 parameters delivered by FIDA. Detection of hydrodynamic radius, changes in hydrodynamic radius and apparent hydrodynamic radius provide the measurements used not only for the Size, but also for Binding & Affinity, Binding Kinetics, Quantity, and Quality parameters, which you can read more about:

Kinetics
Affinity
Quantity
Aggregation
Viscosity
Sample Loss
PDB Correlator
Polydispersity Index
Stickiness
Labelling quality
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